Vitamin D insufficiency defined

VITAMIN D INSUFFICIENCY – HOW IS THIS DEFINED?

The National Osteoporosis Society (NOS) state that in agreement with the Institute of Medicine (IOM), the following vitamin D thresholds are adopted by UK practitioners in respect to bone health1

  • Serum 25OHD < 30 nmol/L is deficient 
  • Serum 25OHD of 30-50 nmol/L may be inadequate in some people 
  • Serum 25OHD > 50 nmol/L is sufficient for almost the whole population

However, it has been argued that levels of at least 75 nmol/L are required to suppress PTH and bone turnover2

Also, it has been argued that serum vitamin D3 in the range of 50-80 nmol/L may be optimal for fracture prevention2

REFERENCES

  1. National Osteoporosis Society (2016). Vitamin D and Bone Health: A Practical Clinical Guideline for Patient Management. Accessed online: www.nos.org.uk/document.doc?id=1352 (April 2016).
  2. European Food Safety Authority (2016). Scientific Opinion on Dietary Reference Values for vitamin D. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA). EFSA Journal. Accessed online: www.efsa.europa.eu/en/press/news/160321a