Why is it important?


Vitamin D controls calcium absorption in the small intestine and works with the parathyroid hormone to mediate skeletal mineralisation and maintain calcium homeostasis in the blood stream1.

There is growing evidence that vitamin D has a non-calcium related, receptor mediated function in muscle cells2,3. Vitamin D receptors have been identified on muscle cells, and the function of muscle tissues are related to vitamin D status, which may explain muscle weakness and fasciculation in the elderly2,3 In addition, muscle mass and the deposition of fat into muscles of young women appear to be related to low vit D status.4

There is tremendous interest in the role of vitamin D, not just for the purpose of maintaining bone health, but also its potential role in the prevention of nonskeletal disorders such as auto-immune disease, cancer, mental health problems and cardiovascular disease.1,2


  1. Kulie T et al. JABFM November-December 2009 Vol. 22 No. 6
  2. Hamilton et al 2010  Scand J Med Sci Sports: 20: 182-190
  3. Lisa Ceglia 2008  Molecular Aspects of Medicine 29 (2008) 407-414
  4. Gilzanse et al 2010 J Clin Endocrinol Metab 95: 1595-1601